CALFIC 200 SYRUP

Calfic syrup is an ideal combination of calcium, iron-folic acid and B12 vitamin. Ferrous Gluconate is formed with iron and gluconic acid. It is only 12 per cent elemental iron. Calcium Gluconate is the calcium salt of gluconic acid, an oxidation product of glucose, and contains 9.3% calcium, which is about one-third of the calcium in the strength of calcium chloride USP. Vitamin B12 has a key role in the normal functioning of the brain and nervous system and in the formation of blood. Folic acid is a form of water-soluble vitamin B9 and is a key factor in the synthesis of nucleic acid (DNA & RNA). It is vital for the production of healthy red blood cells. The use of this compound compared with other iron preparations results in satisfactory reticulocyte responses, a high percentage utilization of iron, and a daily increase in haemoglobin that a normal level occurs in a reasonably short time.

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Product Description

Description: Calfic syrup is a dual-action supplement, combining ferrous gluconate, calcium gluconate, folic acid, and cyanocobalamin, providing a comprehensive source of iron and calcium to support red blood cell production, bone health, and overall nutritional needs.

Pharmaceutical Dosage Form: Syrup

Route of Administration: Oral

Composition:
Each 15ml contains:

Ferrous Gluconate
I.P.
300 mg
Calcium Gluconate
I.P.
125 mg
Vitamin B12
I.P.
10 mcg
Folic Acid
I.P.
2 mg
Sorbitol solution (70%)
q.s.
In a flavoured syrupy base
q.s.

Mechanism of Action: Ferrous gluconate is orally ingested and enters the digestive system. In the acidic environment of the stomach, it undergoes dissolution, releasing ferrous ions (Fe2+). The ferrous ions are then absorbed in the small intestine and converted to the ferric state (Fe3+), which is the form of iron that can be utilized by the body. The absorbed iron is then transported in the bloodstream, primarily bound to transferrin, a transport protein. Iron is a crucial component of hemoglobin, the protein in red blood cells responsible for transporting oxygen. Within the bone marrow, iron is incorporated into protoporphyrin to form heme, which is then combined with globin chains to produce hemoglobin. The newly synthesized hemoglobin is utilized in the formation of red blood cells (erythropoiesis). Ferrous gluconate supports hemoglobin synthesis and red blood cell production, addressing iron-deficiency anemia by improving oxygen transport in the body. Calcium gluconate provides a supplemental source of calcium, crucial for bone health, muscle function, and nerve transmission, contributing to overall skeletal and physiological well-being. Folic acid is essential for DNA synthesis and cell division. Folic acid is particularly important during periods of rapid growth and development. It supports the formation of red blood cells and is crucial for the prevention of neural tube defects during pregnancy. Cyanocobalamin a vital vitamin B12 that plays a key role in the synthesis of DNA, red blood cell formation, and maintenance of the nervous system. Cyanocobalamin is especially important for individuals with B12 deficiency, which can lead to anemia and neurological issues. Sorbitol is a sugar alcohol, and often used as a sweetening agent. Some studies also suggest that sorbitol improves iron absorption in man.

Indications: Calfic syrup is typically indicated for individuals with the following conditions or needs: Iron Deficiency Anemia, Calcium Deficiency, Folic Acid Deficiency, Vitamin B12 Deficiency and General Nutritional Support.

Dosage: As directed by the physician.

Storage: Store at room temperature, away from light and moisture.

Presentation: 200ml bottle

Side effects: Nausea, Constipation, Temporary staining of the teeth, Stomach upset

Contraindications: Calfic syrup is contraindicated in patients with a history of hypersensitivity to the drug or any excipients from the dosage form.

Drug Interactions: Calfic syrup can interact with other drugs. Here are some notable drug interactions: Antacids, Thyroid medications



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