TORQUE’S LINZOLID

Mechanism of Action: Linezolid is a synthetic, antibacterial agent that belongs to a new class of antimicrobials, the oxazolidinones. It has in vitro activity against aerobic Gram positive bacteria and anaerobic micro-organisms. Linezolid selectively inhibits bacterial protein synthesis via a unique mechanism of action. Specifically, it binds to a site on the bacterial ribosome (23S of the 50S subunit) and prevents the formation of a functional 70S initiation complex which is an essential component of the translation process.

Indications: Torque’s Linzolid is indicated for pneumonia, community-acquired pneumonia and Complicated/uncomplicated skin and skin structure infections

Dosage: As directed by the physician.

Storage: Store protected from light & moisture at a temperature not exceeding 30°C

Presentation: 10X1X10 Tablets

Side effects: Dermatitis, Rash, Itching, Blurred vision, Headache, Metallic taste in mouth, Diarrhoea, Nausea, Vomiting, GIT irritation

Contraindications: Torque’s Linzolid is contraindicated in patients with a known allergy to constituents or excipients, during pregnancy and lactation, in patients with severe hepatic failure or renal impairment.

Drug Interactions: Torque’s Linzolid can cause drug interaction with following drugs:

Monoamine oxidase inhibitors (phenelzine, isocarboxazid, selegiline, moclobemide)

Decongestant cold or flu remedies containing pseudoephedrine or phenylpropanolamine.

Anti-asthmatic medicine containing such as salbutamol, terbutaline, fenoterol.

Tricyclics or SSRIs Antidepressants (fluoxetine, fluvoxamine, imipramine, lofepramine, paroxetine, sertraline.)

Medicines used to treat migraine such as sumatriptan and zolmitriptan.

Antihypertensives

Anticoagulant

Rifampin