Product Description
Description: Teneglee 20 Tablets contain teneligliptin which is a dipeptidyl peptidase-4 (DPP-4) inhibitor.
Pharmaceutical Dosage Form: Tablet
Route of Administration: Oral
Composition: Each film coated tablet contains:
Teneligliptin hydrobromide hydrate IP eq. to Teneligliptin 20 mg
Excipients q.s.
Mechanism of Action: The glucagon-like peptide-1 (GLP-1) is secreted from alimentary canal in response to meal that promotes insulin secretion from pancreas and regulates blood sugar post meal by controlling glucagon secretion. Teneligliptin exhibits a hypoglycemic effect by controlling the decomposition of GLP-1 by inhibiting dipeptidyl peptidase-4 (DPP-4) activity and thereby increasing blood concentration of active GLP-1.
Indications: Teneglee 20 is indicated for the treatment of type 2 Diabetes Mellitus as a monotherapy adjunct to diet and exercise.
Dosage: As directed by the physician.
Storage: Store protected from light & moisture at a temperature not exceeding 30°C
Presentation: 10 X 15 Tablets
Side effects: Hypoglycemia, Dizziness, Headache, Constipation, Diarrhoea, Diarrhoea, Abdominal pain, Hepatic steatosis, Rash, Edema.
Contraindications: Teneglee 20 is contraindicated in patients with severe ketosis, diabetic coma or pre-coma, type 1 diabetes, severe trauma, renal failure or acute or chronic disease which may cause tissue hypoxia such as: cardiac or respiratory failure, recent myocardial infarction, shock, hepatic insufficiency, acute alcohol intoxication and alcoholism (due to the metformin component).
Drug Interactions: Teneglee 20 can cause drug interaction with following drugs:
Other antidiabetics
Furosemide
Ketoconazole combination
Class IA anti arrhythmic drugs: Quinidine Sulfate Hydrate, Procainamide Hydrochloride Cholestyramine
Class III antiarrhythmic drugs: Amiodarone Hydrochloride, Sotalol Hydrochloride
β-blocking agents
Salicylic acid drugs
Monoamine oxidase inhibitor
Adrenaline
Adrenocortical hormone
Thyroid hormone
