Product Description
Description: Torque’s Torvator F Tablets contain atorvastatin which is a synthetic lipid-altering agent and Fenofibrate which is a peroxisome proliferator receptor alpha (PPARα) activator.
Pharmaceutical Dosage Form: Tablet
Route of Administration: Oral
Composition: Each film-coated tablet contains:
Atorvastatin Calcium eq. to Atorvastatin 10 mg
Fenofibrate I.P. (Micronized) 160 mg
Mechanism of Action: Atorvastatin is a selective, competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, the rate-limiting enzyme that converts HMG-CoA to mevalonate. Atorvastatin reduces low density lipoprotein (LDL) production and the number of LDL particles. Fenofibrate increases lipolysis and elimination of triglyceride-rich particles from plasma by activating lipoprotein lipase and reducing production of apoprotein C-III (an inhibitor of lipoprotein lipase activity).
Indications: Torque’s Torvator F is indicated as an adjunct to diet to reduce elevated total C, LDL-C, apo B, and TG levels and to increase HDL-C in adult patients with primary hypercholesterolemia (heterozygous familial and nonfamilial) and mixed dyslipidemia (Fredrickson Types II and II b)
Dosage: As directed by the physician.
Storage: Store at a temperature not exceeding 30°C. Protect from light & moisture
Presentation: 10X10 Tablets
Side effects:
Muscle pain
Headache
Joint Pain
Urinary Tract Infection
Constipation
Flatulence
Dyspepsia
Nausea
Diarrhea
Weakness
Contraindications: Torque’s Torvator F is contraindicated in patients with a known allergy to constituents or excipients, during pregnancy and lactation, in patients with severe hepatic failure or renal impairment.
Drug Interactions: Torque’s Torvator F can cause drug interaction with following drugs:
Cyclosporine
Clarithromycin
Azole Antifungals
Protease Inhibitors (Tipranavir Plus Ritonavir, Telaprevir, Lopinavir, Etc)
CYP3A4 Inhibitors(e.g. Erythromycin, Diltiazem, Verapamil and Fluconazole)
Inducers of CYP3A4 (e.g. Efavirenz, Rifampin, St. John’s Wort)
Fibric Acid Derivatives, Erythromycin, Lipid-Modifying Doses of Niacin, Colchicine
Oral Contraceptives & Warfarin
