Product Description
Description: Ceftorque T 1.125 is sterile, semisynthetic, broad-spectrum antibiotic for intravenous or intramuscular administration. It consists of ceftriaxone which is a 2-aminothiazolyl methoxylmino third-generation cephalosporin derivative and tazobactam is a penicillinate sulphone, beta lactamase inhibitor structurally related to sulbactam.
Pharmaceutical Dosage Form: Dry Injection
Route of Administration: Intravenous & Intramuscular
Composition: Each vial contains:
Ceftriaxone Sodium (Sterile) IP Eq. to Anhydrous Ceftriaxone 1000 mg
Tazobactam Sodium (Sterile) IP Eq. to Tazobactam 0.125 mg
Mechanism of Action. Ceftriaxone inhibits bacterial cell wall synthesis following attachment to penicillin-binding proteins (PBPs). This results in the interruption of cell wall (peptidoglycan) biosynthesis, which leads to bacterial cell lysis and death. Tazobactam acts synergistically with many beta lactamase labile drugs such as penicillins and cephalosporin’s. The combination of tazobactam and ceftriaxone is active against all the organism’s sensitive to ceftriaxone.
Indications: Ceftorque T 1.125 is used to treat Lower respiratory tract infections and community acquired pneumonia, Acute bacterial otitis media, Skin and skin structure infections, Urinary tract infections, Uncomplicated gonorrhoea, Pelvic inflammatory disease, Bacterial septicemia, Bone and joint infections, Intra-abdominal infections, and Bacterial meningitis.
Dosage: As directed by the physician.
Storage: Store protected from moisture, at a temperature not exceeding 25°C.
Presentation: Glass Vial
Side effects:
Decreased leucocytes
Increased eosinophil
Decreased thrombocytes
Pruritus
Diarrhea
Nausea
Vomiting
Contraindications: Ceftorque T 1.125 is contraindicated in patients with known or suspected hypersensitivity to the drug or any of the excipients, during pregnancy and lactation, in patients with severe hepatic failure or renal impairment.
Drug Interactions: Ceftorque T 1.125 can cause drug interaction with following drugs:
Vancomycin
Oral anticogulants
Fluconazole
Interaction with Calcium-containing Products
Chloramphenicol
