Product Description
DESCRIPTION:
Clob-GM is a skin ointment. A combination of Clobetasol Propionate, Miconazole Nitrate, Neomycin & Chlorhexidine Gluconate. Clobetasol Propionate is a highly active corticosteroid. Neomycin is an aminoglycoside antibiotic. Miconazole is an imidazole antifungal agent. Chlorhexidine gluconate is an antimicrobial agent.
PACKING:
15GM Tube
COMPOSITION:
|
Clobetasol Propionate
|
I.P
|
0.05 w/w
|
| Neomycin Sulphate |
I.P.
|
|
| Miconazole Nitrate |
I.P.
|
2.0% w/w
|
| Equivalent to Neomycin | 0.5% w/w | |
| Zinc Sulphate | I.P. | 2.0% w/w |
MECHANISM OF ACTION:
Clobetasol Propionate has topical anti-inflammatory activity. The major effect on the skin is a non-specific anti-inflammatory response, partially due to vasoconstriction and a decrease in collagen synthesis. Neomycin is a broad-spectrum antibiotic. Miconazole works by inhibiting the synthesis of ergosterol, a critical component of fungal cell membranes. Chlorhexidine is a bisbiguanide disinfectant that is effective against a wide range of vegetative gram-positive and gram-negative bacteria.
INDICATIONS:
Corticosteroid-responsive dermatoses, eczema and psoriasis.
CONTRAINDICATIONS:
Long-term treatment of ulcerative conditions, rosacea, pruritus, presence of acute infections. Hypersensitivity.
SIDE EFFECTS:
Prolonged usage of a large amount of Clobetasol Propionate can lead to sufficient systemic levels to produce adrenal suppression, Cushing’s syndrome, diabetes and hypertension.
DIRECTIONS:
To be applied as directed by the physician.
STORAGE:
Store at a temperature below 25, Do not freeze. Keep all medicines out of the reach of children.
