DESCRIPTION:Clob-GM is a skin ointment. A combination of Clobetasol Propionate, Miconazole Nitrate, Neomycin & Chlorhexidine Gluconate. Clobetasol Propionate is a highly active corticosteroid. Neomycin is an aminoglycoside antibiotic. Miconazole is an imidazole antifungal agent. Chlorhexidine gluconate is an antimicrobial agent.PACKING: 15GM Tube
COMPOSITION:
Clobetasol Propionate
I.P
0.05 w/w
Neomycin Sulphate
I.P.
Miconazole Nitrate
I.P.
2.0% w/w
Equivalent to Neomycin
0.5% w/w
Zinc Sulphate
I.P.
2.0% w/w
MECHANISM OF ACTION:Clobetasol Propionate has topical anti-inflammatory activity. The major effect on the skin is a non-specific anti-inflammatory response, partially due to vasoconstriction and a decrease in collagen synthesis. Neomycin is a broad-spectrum antibiotic. Miconazole works by inhibiting the synthesis of ergosterol, a critical component of fungal cell membranes. Chlorhexidine is a bisbiguanide disinfectant that is effective against a wide range of vegetative gram-positive and gram-negative bacteria.INDICATIONS:Corticosteroid-responsive dermatoses, eczema and psoriasis.CONTRAINDICATIONS:Long-term treatment of ulcerative conditions, rosacea, pruritus, presence of acute infections. Hypersensitivity.SIDE EFFECTS:Prolonged usage of a large amount of Clobetasol Propionate can lead to sufficient systemic levels to produce adrenal suppression, Cushing’s syndrome, diabetes and hypertension.DIRECTIONS:To be applied as directed by the physician.STORAGE:Store at a temperature below 25, Do not freeze. Keep all medicines out of the reach of children.
