HEMOPLUS-XT TABLETS

COMPOSITION:
Each film-coated contains:
Ferrous Ascorbate
Equivalent to Elemental Iron                               100mg Folic Acid                                       I.P.                     1.5mg Appropriate overages of vitamin added.

DESCRIPTION:
Ferrous Ascorbate is obtained by reacting ascorbic acid and iron. It has excellent absorption as ascorbic acid enhances the absorption of iron. Ascorbic acid reduces ferric iron to ferrous iron which remains soluble even at neutral pH. Folic Acid is a form of water-soluble vitamin B9 and is a key factor in the synthesis of nucleic acid (DNA & RNA). It is vital for the production of healthy red blood cells.

MECHANISM OF ACTION:
Ferrous Ascorbate when administered is converted to ferric form and immediately is reduced to the ferrous form in the stomach. This reduced ferrous form is then transferred to the duodenum where it is highly absorbed. Ferrous Ascorbate has the advantage of providing both ferrous ion and ascorbate in the same compound. There is no dissociation on entering the GI Tract due to the stable chelate of iron with ascorbate. Folic Acid itself is biochemically inactive, is converted to tetrahydrofolic acid and methyltetrahydrofolate by dihydrofolate reductase in the liver. These folic acid congeners are transported across cells by receptor-mediated endocytosis where they are needed to maintain numerous body functions.

INDICATIONS:
Indicated in the treatment of iron deficiency anaemia, menorrhagia and folate deficiency anaemia.
Ferrous ascorbate reduces the risk of pre-eclampsia (pregnancy-induced hypertension) which generally occurs in severe or very severe anaemia. Folic acid can reduce the risk of fetal neural tube defects.

CONTRAINDICATIONS:
Hypersensitivity to iron should be avoided in patients who have bacterial infections. Contraindicated in patients who have hemosiderosis, hemochromatosis, and hemolytic anaemia.

DRUG INTERACTIONS:
Iron compounds taken orally can impair the absorption of tetracycline antibiotics. Antacids given concomitantly with iron compounds decrease iron absorption.

SIDE EFFECTS:
Nausea, regurgitation, constipation, pyrosis (burning sensation in the chest), an upset stomach may occur with the use of hematinics.
Iron may cause your stools to turn black, an effect that is not harmful.

PRECAUTIONS:
Oral iron may aggravate existing peptic ulcers, regional enteritis and ulcerative colitis.

DOSAGE:
As directed by the physician.

STORAGE:
Store in a cool & dark place.
Keep out of the reach of the children.

PRESENTATION: 10×10 tablets in a cardboard carton