Description: Kofnil Syrup is a combination of an antihistamine, a cough suppressant, and a decongestant, which is used in the treatment of dry cough and congestion. It is highly effective in relieving the body's allergy-like symptoms such as a runny nose, cough, sneezing, stuffy nose, itching, and watery eyes.
Dosage Form: Syrup
Route of Administration: Oral
Composition: Each 5ml contains:
Dextromethorphan Hydrobromide I.P. 10mg
Phenylephrine HCl I.P. 5mg
Chlorpheniramine Maleate I.P. 2mg
Flavoured Syrup Base q.s.
Mechanism of Action: Kofnil Syrup is a combination of an antihistamine (Chlorpheniramine), a cough suppressant (dextromethorphan) and a decongestant (phenylephrine). Chlorpheniramine is an antihistamine that works by blocking the action of histamine, a substance in the body that contributes to allergy symptoms. By inhibiting histamine, chlorpheniramine reduces the effects of allergic reactions, such as sneezing, itching, and watery eyes. Dextromethorphan is a cough suppressant that affects the cough center in the brain. It works by decreasing the urge to cough, providing relief from dry or unproductive coughing without causing the sedative effects. Phenylephrine is a nasal decongestant that works by narrowing the blood vessels in the nasal passages. This constriction reduces swelling and congestion in the nasal tissues, making it easier to breathe. It is commonly used to relieve nasal congestion associated with conditions like the common cold or allergies. Together, these three components in a combination medication aim to address multiple symptoms associated with coughs and colds, including allergy-related symptoms, coughing, and nasal congestion.
Indications: Kofnil Syrup is used to treat dry cough and congestion. It also relieves allergy symptoms like watery eyes, sneezing, runny nose, and throat irritation.
Dosage: As directed by the physician.
Side effects: Dizziness, Drowsiness, Blurred vision, Dry mouth, Loss of appetite, and Nausea.
Contraindications: Kofnil Syrup is contraindicated in patients with a history of hypersensitivity to the drug or any excipients from the dosage form.
Drug Interactions: Kofnil Syrup can interact with other drugs. Here are some notable drug interactions with this medication: Isocarboxazid, Metaxalone, Methylene blue, Rasagiline, Safinamide, Selegiline.
Storage: Store at a temperature not exceeding 25 °C. Protect from sunlight, heat & moisture.
Presentation: 60ml & 100ml bottle.