Nortor-TZ Tablets

Description: Nortor-TZ Tablets contain Norfloxacin is a broad-spectrum antibacterial agent and tinidazole is a synthetic antiprotozoal and antibacterial agent that are used to treat diarrhea and dysentery. Pharmaceutical Dosage Form: Tablet Route of Administration: Oral Composition:

Mechanism of Action: Norfloxacin is a fluoroquinolone antibiotic. It inhibits bacterial DNA gyrase, an enzyme essential for DNA replication, transcription, repair, and recombination in bacteria. By inhibiting DNA gyrase, Norfloxacin interferes with the process of bacterial DNA synthesis and leads to the death of susceptible bacteria. Tinidazole inhibits the growth of protozoa by interacting with the DNA of the micro-organism and inhibiting the protein synthesis, thereby leading to death of the micro-organism. Indications: Nortor-TZ Tablets are indicated for the treatment of diarrhoea and dysentery of amoebic, bacterial or mixed origins. Dosage: As prescribed by the physician. Storage: Store at a temperature not exceeding 25°C. Protect from light and moisture. Presentation: 10 x 4 x 10 Tablets Side effects: Dizziness Nausea Headache Abdominal Cramping Weakness Fatigue Malaise Anorexia Diarrhoea Contraindications: In patients with a history of hypersensitivity, tendinitis, or tendon rupture associated with the use of norfloxacin or any member of the quinolone group of antimicrobial and tinidazole or other nitroimidazole derivatives. In pregnancy and during lactation In patients having, or with a history of, blood dyscrasia, although no persistent haematological abnormalities have been noted in clinical or animal studies. Drug Interactions: Nortor-TZ tablets should not be taken with the following medicines due to severe side effects – Caffeine Clozapine Ropinirole Tacrine Tizanidine Theophylline Cyclosporine Anticoagulants Glyburide Probenecid Nitrofurantoin Alcohol, Disulfiram Phenytoin, Fosphenytoin Cyclosporine, Tacrolimus