DESCRIPTION: Dermitor-KT 5+ is a multifunctional dermatological combination cream featuring ketoconazole, iodochlorhydroxyquinoline, tolnaftate, neomycin sulphate, clobetasol propionate, and dexpanthenol designed to address a spectrum of skin conditions with antifungal, antibacterial, and anti-inflammatory properties.
DOSAGE FORM: Cream
ROUTE OF ADMINISTRATION: Topical
COMPOSITION:
Each gm contains:
| Ketoconazole | I.P. | 2.00%w/w |
| Iodochlorhydroxyquinoline | I.P. | 1.0%w/w |
| Tolnaftate | I.P. | 1.00%w/w |
| Neomycin Sulphate eq. to Neomycin | I.P. | 0.1%w/w |
| Clobetsol Propionate | I.P. | 0.005%w/w |
| Dexpanthenol | I.P. | 0.5%w/w |
| In a Cream base | q.s. |
MECHAMISM OF ACTION: Ketoconazole is an antifungal medication that inhibits the synthesis of ergosterol, a crucial component of the fungal cell membrane, disrupting fungal cell structure and function. Iodochlorhydroxyquinoline has antibacterial and antifungal properties, acting by disrupting the integrity of microbial cell membranes and interfering with essential cellular processes. Tolnaftate is an antifungal agent, interferes with fungal cell membrane function, disrupting the synthesis of ergosterol, which is essential for the integrity of fungal cell membranes. Neomycin is an antibiotic, inhibits bacterial protein synthesis by binding to the bacterial ribosome, leading to the disruption of protein production and ultimately bacterial cell death. Clobetasol is a potent corticosteroid, clobetasol reduces inflammation by inhibiting the release of inflammatory mediators and suppressing the immune response, providing relief from itching, redness, and swelling associated with various skin conditions. Dexpanthenol is a precursor of vitamin B5 (pantothenic acid) and is known for its moisturizing properties. It is converted to pantothenic acid in the skin, which plays a role in cell regeneration and wound healing.
INDICATIONS: Dermitor-KT 5+ cream is used to treat mixed skin infections (fungal & bacterial) with itching and dryness.
DOSAGE: As prescribed by the physician
CAUTION: Patients with a history of hypersensitivity or allergic reactions to any of the components in the combination should avoid its use.
PACKING: 34x15gm tube