CIPROMAC-D E/E DROPS

Description: Cipromac-D eye/ear drops is a combination of an antibiotic (ciprofloxacin) and a corticosteroid (dexamethasone) medication used to treat bacterial infections and reduce inflammation in the eyes or ears. The antibiotic inhibits bacterial growth, while the corticosteroid alleviates swelling, redness, and discomfort associated with inflammation. This combination is commonly used to manage conditions such as bacterial conjunctivitis or otitis externa, providing a dual-action approach for effective treatment.

Dosage Form: Eye/Ear Drops

Route of Administration: Ocular/Otic

Composition:

Ciprofloxacin Hydrochloride (eq. to Ciprofloxacin)        I.P.          0.3% w/v

Dexamethasone                                                                 I.P.          0.1% w/v

Benzalkonium Chloride Solution (Preservative)              I.P.          0.02% v/v

Sterile aqueous buffered vehicle                                                      q.s.

Mechanism of Action: Ciprofloxacin inhibits bacterial growth by targeting DNA gyrase, an essential enzyme involved in DNA replication, thereby disrupting bacterial DNA synthesis and exerting a bactericidal effect. Dexamethasone, a corticosteroid, exerts its mode of action by suppressing inflammation and immune responses through the inhibition of pro-inflammatory mediators, such as cytokines and prostaglandins, leading to anti-inflammatory and immunosuppressive effects.

Indications: Cipromac-D eye/ear drops is used to treat infections in the eye or ear caused by bacteria.

Dosage: As prescribed by the physician.

Side effects:  Local irritation, Itching sensation, Blurred vision, burning sensation, Ocular hyperemia, Taste change, Ear pain

Contraindications: Cipromac-D eye/ear drops is contraindicated in certain situations. Contraindications may include –

1. Individuals who have a known hypersensitivity or allergic reaction to ciprofloxacin, dexamethasone, or any other components of the eye/ear drops should avoid using the medication.
2. Cipromac-D eye/ear drops is generally not recommended for the treatment of viral infections.
3. Cipromac-D eye/ear drops is generally not recommended for the treatment of fungal infections.            Precautions & Warnings:
4. Prolonged use may result in overgrowth of non-susceptible organisms, including fungi. If a secondary infection occurs during treatment, the use of the drops should be reassessed.
5. Contact lenses should be removed before applying the drops, and reinsertion should be delayed for at least 15 minutes or as directed by a healthcare professional.
6. Corticosteroids, like dexamethasone, may delay wound healing and increase the risk of corneal perforation. Caution is advised in patients with corneal ulcers.
7. The potential risks and benefits of using Cipromac-D eye/ear drops during pregnancy or breastfeeding should be discussed with a healthcare provider.                                                                                                              Storage: Store in a cool and dry place away from direct sunlight.                                                        Presentation: 10ml vial

BARCODE: 0108906044105270 0118906044105277 0128906044105274