Description: Fiximac-O Tablet combines Cefixime and Ofloxacin to effectively treat a range of bacterial infections, including respiratory, urinary, and gastrointestinal infections. It works by inhibiting bacterial growth and preventing DNA replication. Pharmaceutical Dosage Form: Tablet Route of Administration: Oral Composition: Each film coated tablet contains: Cefixime (as Trihydrate) I.P. Eq. to Anhydrous Cefixime 200mg Ofloxacin I.P. 200mg Excipients q.s. Colour: Tartrazine & Titanium Dioxide I.P. Mechanism of Action: Cefixime exerts its antibacterial action by inhibiting the synthesis of bacterial cell walls through binding to penicillin-binding proteins, disrupting the formation of the cell wall and leading to bacterial cell death. Ofloxacin inhibits bacterial DNA replication by inhibiting bacterial topoisomerases, particularly DNA gyrase and topoisomerase IV. Indications: Fiximac-O Tablet is used for the treatment of patients with typhoid fever and urinary tract infection in adults. Dosage: As prescribed by the physician. Storage: Protect from light and store below 300 Presentation: 10X1X10 Tablets Side effects: Nausea Abdominal pain Allergy Diarrhea Stomach pain Contraindications: Fiximac-O Tablet is contraindicated in patients with a known allergy to Cefixime/ Ofloxacin or to the Cephalosporin/ fluoroquinolone group of antibiotics. Drug Interactions: Fiximac-O Tablet can interact with other drugs, potentially affecting their efficacy or increase the risk of side effects. Some notable drug interactions include – Cefixime: BCG Vaccine live Cholera vaccine Typhoid live vaccine Antacids and H2 blockers Probenecid Nephrotoxic drugs Warfarin Oral contraceptives Ofloxacin Antacids, Sucralfate, Metal Cations Theophylline, fenbufen or similar non-steroidal anti-inflammatory drugs Antiarrhythmics, Tricyclic Antidepressants, macrolides, and antipsychotics Probenecid, cimetidine, furosemide, and methotrexate Vitamin K antagonists