DESCRIPTION: Gencin-B eye/ear drops is a medication that combines the anti-inflammatory effects of betamethasone, with the antibacterial actions of gentamicin. This combination is used to treat various inflammatory eye or ear conditions, such as infections or allergies, by reducing inflammation and controlling bacterial growth.
DOSAGE FORM: Eye/ Ear Drops
ROUTE OF ADMINISTRATION: Topical
COMPOSITION:
|
Gentamicin sulphate equ to gentamicin base (3000 units/ml) |
IP |
0.3%w/v |
|
Betamethasone sodium phosphate |
IP |
0.1%w/v |
|
Benzalkonium chloride Solution (as preservative) |
IP |
0.02%w/v |
|
Sterile aqueous buffered vehicle |
q.s. |
MECHANISM OF ACTION: The bactericidal action of gentamicin is based on an irreversible inhibition of the bacterial protein synthesis. Gentamicin elicits rapid bacterial action by acting directly on the bacterial ribosome, where it disrupts the normal cycle of ribosomal function. Additionally, gentamicin includes misreading the genetic code of the mRNA template, leading to the incorporation of incorrect amino acids into the growing polypeptide chain. Betamethasone sodium phosphate is a potent glucocorticoid steroid with anti-inflammatory and immunosuppressive properties.
INDICATIONS: Used in bacterial eye infections and ear infections.
DOSAGE: As directed by the physician.
DIRECTIONS: Use the solution within one month after opening the container.
SIDE EFFECTS: Eye stinging/burning/redness or temporary blurred vision may occur, raised intraocular pressure.
CONTRAINDICATIONS: Known hypersensitivity to gentamicin or any ingredient in the formulation & patients with fungal infections.
DRUG INTERACTIONS: Other drugs, especially those that affect the kidneys, can interact with gentamicin resulting in dangerous side effects and/or decreased effectiveness. Do not take any other prescription or over-the-counter medicines, including vitamins, minerals, and herbal products, without first talking to your doctor during treatment with gentamicin.
WARNING: 1. If irritation persists or increases, discontinue the use and consult the physician. 2. Do not touch the dropper tip to any surface as this may contaminate the solution.
STORAGE: Store in a cool, dry place. Protect from light.
PRESENTATION: 576x10 ml
BARCODE: 0108906044106055 0118906044106052 0128906044106059