DESCRIPTION: Ambroxol Hydrochloride is the metabolite of bromhexine and a mucolytic agent. Ambroxol acts as secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. Cetirizine is a second-generation antihistamine used in the treatment of allergies, hay fever, angioedema, and urticaria. It is a major metabolite of hydroxyzine and a racemic selective H1 receptor inverse agonist. PACKING: 60x20x10 tablets COMPOSITION: Each film-coated tablet contains:
|
Cetirizine Hydrochloride |
I.P. |
5 mg |
|
Ambroxol Hydrochloride |
I.P. |
60 mg |
MECHANISM OF ACTION: Ambroxol facilitates mucociliary clearance by intensifying the motion of the cilia present on the ciliated respiratory epithelium. Cetirizine competes with histamine for binding at H1-receptor sites on the effector cell surface, resulting in suppression of histaminic edema, flare, and pruritus. It crosses the blood-brain barrier only slightly, reducing the sedative side-effect common with older antihistamines. INDICATIONS: Seasonal/allergic rhinitis, nasal discomfort, body ache, stubborn cough. CONTRAINDICATIONS: Hypersensitivity to any ingredient of the product. WARNING: Do not exceed recommended dosage. DOSAGE: As directed by the physician. STORAGE: Store in a cool & dry place. Protect from light. PRESENTATION: 20×10 tablets in a cardboard carton