1. Description: Torque’s Orthomac Plus tablet is a medication that combines diclofenac sodium and paracetamol to provide a dual-action approach for pain relief.
2. Pharmaceutical Dosage Form: Tablet
3. Route of Administration: Oral
4. Composition: Each uncoated tablet contains:
Diclofenac Sodium I.P. 50mg
Paracetamol I.P. 325mg
Excipients q.s.
5. Mechanism of Action: Diclofenac sodium is a non-steroidal anti-inflammatory drug (NSAID) that exhibits anti-inflammatory, analgesic and anti-pyretic activity. It’s primarily inhibits the enzyme cyclooxygenase (COX). COX is involved in the synthesis of prostaglandins, which are substances in the body that mediate inflammation, pain, and fever. By inhibiting COX, diclofenac sodium reduces the production of prostaglandins, thereby mitigating inflammation, relieving pain, and lowering fever. This anti-inflammatory and analgesic effect makes diclofenac sodium commonly used in the treatment of conditions such as arthritis, musculoskeletal pain, and inflammatory disorders. Paracetamol is an analgesic and antipyretic drug that is used to relieve mild-to-moderate pain and fever. It inhibits the enzyme cyclooxygenase (COX) in the central nervous system, reducing the production of prostaglandins and providing analgesic (pain-relieving) and antipyretic (fever-reducing) effects. This combination is commonly prescribed for various conditions involving moderate to severe pain, offering a synergistic effect to enhance overall efficacy.
6. Indications: Torque’s Orthomac Plus tablet is used for pain relief. It relieves pain in conditions like headache, mild migraine, muscle pain, dental pain, rheumatoid arthritis, ankylosing spondylitis, osteoarthritis, and painful menses.
7. Dosage: As directed by the physician.
8. Storage: Store in a dry place, protect from sunlight.
9. Presentation: 20 x 2 x 10 tablets.
10. Side effects:
Nausea
Vomiting
Abdominal pain
Flatulence
Diarrhea
11. Contraindications: Torque’s Orthomac Plus tablet is contraindicated in patients with a history of hypersensitivity to the drug or any excipients from the dosage form.
12. Drug interactions: Torque’s Orthomac Plus tablet can interact with other drugs. Here are some notable drug interactions with this medication:
Aspirin
Tramadol
Digoxin
Oxycodone
Cimetidine
Warfarin
Phenytoin
