Product Description
Description: Torque’s Pantotor-DSR capsules is a medication in sustained release pellets form combining pantoprazole, a proton pump inhibitor, and domperidone, a prokinetic agent, to treat conditions related to excessive stomach acid and gastrointestinal motility disorders.
Pharmaceutical Dosage Form: Capsule
Route of Administration: Oral
Composition: Each hard gelatin capsule contains:
| Pantoprazole Sodium (as enteric coated pellets) | I.P. | |
| Eq. to Pantoprazole | 40mg | |
| Domperidone (as sustained release pellets) | I.P. | 30mg |
| Excipients | q.s. |
Mechanism of Action: Pantoprazole is a first-generation proton pump inhibitor (PPI) used for the management of gastroesophageal reflux disease (GERD). Pantoprazole binds irreversibly and specifically to the proton pump, thereby reducing gastric acid secretion. Pantoprazole has a relatively long duration of action compared with other PPIs, and a lower propensity to become activated in slightly acidic body compartments. Domperidoneis a dopamine receptor antagonist used as a peristaltic stimulant and anti-emetic agent for dyspepsia, indigestion, epigastric pain, nausea, and vomiting. It provides relief from nausea by blocking receptors at the chemoreceptor trigger zone. Domperidone is a prokinetic which works on the upper digestive tract to increase the movement of the stomach and intestines, allowing the food to move more easily through the stomach.
Indications: Torque’s Pantotor-DSR capsules is used to treat gastro-esophageal reflux disease (GERD), acidity, and indigestion.
Storage: Store protected from light & moisture, at a temperature not exceeding 25ºC.
Presentation: 20 x 10 capsules
Side effects:
Nausea
Headache
Stomach pain
Dry mouth
Diarrhea
Contraindications: Torque’s Pantotor-DSR capsules is contraindicated in patients with a history of hypersensitivity to the drug or any excipients from the dosage form.
Drug Interactions: Torque’s Pantotor-DSR capsule can interact with other drugs. Here are some notable drug interactions:
Atazanavir
Nelfinavir
Digoxin
Rifampicin
Warfarin
Methotrexate
Itraconazole
Ketoconazole
Mycophenolate mofetil
ADR: Proton pump inhibitors can cause acute Kidney injury as an adverse drug reactions.
